NexGard COMBO Cat Topical

This prescription medication requires a current annual service visit to a Penny Paws clinic.




What is Nexgard COMBO for Cats?

NexGard Combo is an antiparasitic veterinary medicine that offers the broadest spectrum protection on the market for kittens (from eight weeks/1.8lbs) and adult cats.  It kills fleas and ticks, prevents heartworm disease, and treats and controls hookworms, roundworms and tapeworms. NexGard® COMBO topical solution is parasite protection for cats from the maker of vet-recommended NexGard® (afoxolaner) and HEARTGARD® Plus (ivermectin/pyrantel).

Active ingredients

esafoxolaner, eprinomectin, praziquantel

How do you apply NexGard COMBO?

Nexgard COMBO comes in an easy-to-apply applicator.  To administer:
1. Pull plunger back slightly before removing the cap.
2. Part the hair along the midline of the neck between the base of      the skull and the shoulder blades.
3. Place the applicator tip directly on the exposed skin and apply        the contents. 
*see product label for more details


Esafoxolaner, one of the ingredients in NexGard® COMBO, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in cats receiving isoxazoline class drugs, even in cats without a history of seizures. Use with caution in cats with a history of seizures or neurologic disorders. Do not administer orally. Cats may salivate excessively if NexGard® COMBO is accidentally administered orally or is ingested through licking/grooming the application site. The safety of NexGard® COMBO has not been tested in breeding, pregnant, or lactating cats. The safety of NexGard® COMBO has not been tested in kittens less than 8 weeks of age or weighing less than 1.8 lbs. (0.8 kg)

Storage Instructions

Store at 59°–86°F (15°–30° C). Brief periods up to 104°F (40°C) are permitted. Protect from light.

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